exemestane

Ligand id: 7073

Name: exemestane

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 34.14
Molecular weight 296.18
XLogP 3.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at Human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
CYP19A1 Inhibitor Inhibition 7.3 pIC50 - 1
pIC50 7.3 (IC50 5.01x10-8 M) [1]
Description: Inhibition of aromatase (CYP19A1) extracted to homogeneity from human placenta.