azelastine

Ligand id: 7121

Name: azelastine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 23.55
Molecular weight 381.16
XLogP 5.37
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
H1 receptor Antagonist Antagonist 8.9 pKi - 1
pKi 8.9 (Ki 1.26x10-9 M) [1]