carprofen

Ligand id: 7141

Name: carprofen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 53.09
Molecular weight 273.06
XLogP 3.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
COX-2 Inhibitor Inhibition 7.0 pIC50 - 1
pIC50 7.0 (IC50 1.02x10-7 M) [1]
Description: Inhibition of COX-2-induced conversion of arachadonic acid to 12-HHT.