Synonyms: Phenurone®
phenacemide is an approved drug (FDA (1951))
Compound class:
Synthetic organic
Comment: Phenacemide is a ureide (acetylurea) anticonvulsant. It is a congener and ring-opened analogue of the hydantoin phenytoin, and is structurally related to the barbiturate family of drugs and other hydantoins. Use of phenacemide was widely discontinued due to toxic side-effects.
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Bioactivity Comments |
Due to the complex and varied nature of the precise subunit composition of sodium channels receptors, and a paucity of affinity data with definitive molecular details, we have not tagged a primary target for this drug. |