ticlopidine

Ligand id: 7307

Name: ticlopidine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 31.48
Molecular weight 263.05
XLogP 4.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
If this compound is a prodrug it may have little or no measurable bioactivity at the molecular target of its active counterpart, and as we have been unable to find publicly available bioactivity data at P2RY12 we have not tagged a primary drug target.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
CYP2B6 Hs Inhibitor Inhibition 6.7 pIC50 - 1
pIC50 6.7 (IC50 2x10-7 M) [1]