lenalidomide

Ligand id: 7331

Name: lenalidomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 95.99
Molecular weight 259.1
XLogP 0.2
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Lenalidomide displaces a Cy5-conjugated cereblon modulating compound from the binding pocket of CRBN with an IC50 of 1500nM [1].