metreleptin

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metreleptin

GtoPdb Ligand ID: 7333

Synonyms: Myalept® | r-metHuLeptin | R-methuleptin

metreleptin is an approved drug (FDA (2014), EMA (2018))

Compound class: Peptide or derivative

Comment: Metreleptin is a recombinant, 147 amino acid (~16kDa), N-methionyl- analogue of human leptin [1]. Leptin is an adipokine (cytokine secreted by adipose tissue).

Summary
Biological activity
Clinical data
References
Structure
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Bioactivity Comments
We have been unable to find publicly available affinity data for this drug at its proposed molecular target to substantiate its MMOA, and have therefore not tagged a primary drug target.

Bioactivity Comments

We have been unable to find publicly available affinity data for this drug at its proposed molecular target to substantiate its MMOA, and have therefore not tagged a primary drug target.