cannabinol

Ligand id: 740

Name: cannabinol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 29.46
Molecular weight 310.19
XLogP 7.26
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
CB1 receptor Hs Agonist Partial agonist 6.0 – 6.5 pKi - 1,3
pKi 6.0 – 6.5 [1,3]
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
TRPV2 Rn Activator Activation 4.1 pEC50 - 2
pEC50 4.1 (EC50 7.7x10-5 M) [2]