rimonabant

Ligand id: 743

Name: rimonabant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 50.16
Molecular weight 462.08
XLogP 5.34
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
CB1 receptor Antagonist Antagonist 7.9 – 8.7 pKi - 2-3,5-7
pKi 7.9 – 8.7 (Ki 1.26x10-8 – 1.99x10-9 M) [2-3,5-7]
GPR55 Antagonist Antagonist 5.3 – 6.6 pEC50 - 1,4
pEC50 5.3 – 6.6 (EC50 5.5x10-6 – 2.8x10-7 M) [1,4]
Ligand mentioned in the following text fields