pramlintide

Ligand id: 7482

Name: pramlintide

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
AMY1 receptor Agonist Agonist 9.4 – 9.4 pEC50 - 1
pEC50 9.4 – 9.4 (EC50 4.36x10-10 – 3.55x10-10 M) [1]
Description: Measuring ligand-induced cAMP production in COS and HEK293 cells.
AMY3 receptor Agonist Agonist 9.1 – 9.3 pEC50 - 1
pEC50 9.1 – 9.3 (EC50 8.91x10-10 – 5.2x10-10 M) [1]
Description: Measuring ligand-induced cAMP production in COS and HEK293 cells.
AMY2 receptor Agonist Agonist 8.6 – 8.9 pEC50 - 1
pEC50 8.6 – 8.9 (EC50 2.29x10-9 – 1.38x10-9 M) [1]
Description: Measuring ligand-induced cAMP production in COS and HEK293 cells.
CT receptor Agonist Agonist 8.3 pEC50 - 1
pEC50 8.3 (EC50 5.495x10-9 M) [1]
Description: Measuring ligand-induced cAMP in COS and KEK293 cells.