Ligand id: 7498

Name: bufexamac

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 58.56
Molecular weight 223.12
XLogP 2.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
histone deacetylase 6 Hs Inhibitor Inhibition 5.0 pKd - 1
pKd 5.0 (Kd 1.07x10-5 M) [1]
histone deacetylase 10 Hs Inhibitor Inhibition 4.9 pKd - 1
pKd 4.9 (Kd 1.23x10-5 M) [1]