compound 38 [PMID: 24000170]

Ligand id: 7522

Name: compound 38 [PMID: 24000170]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 90.14
Molecular weight 400.15
XLogP 4.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
bromodomain containing 3 Inhibitor Inhibition 6.6 pIC50 - 1
pIC50 6.6 (IC50 2.51x10-7 M) [1]
bromodomain containing 4 Inhibitor Inhibition 6.5 pIC50 - 1
pIC50 6.5 (IC50 3.16x10-7 M) [1]
bromodomain containing 2 Inhibitor Inhibition 6.3 pIC50 - 1
pIC50 6.3 (IC50 5.01x10-7 M) [1]