pipotiazine

Ligand id: 7557

Name: pipotiazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 97.77
Molecular weight 475.2
XLogP 3.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
D2 receptor Antagonist Antagonist 9.7 pKi - 1
pKi 9.7 (Ki 2x10-10 M) [1]