CCL5

Ligand id: 758

Name: CCL5

Species: Human

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
CCR1
CCR3
CCR5
CXCR3
GPR75
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCR5 Hs Agonist Full agonist 9.2 – 9.7 pKi - 1,7-8
pKi 9.2 – 9.7 [1,7-8]
CCR3 Hs Agonist Full agonist 8.5 – 9.3 pKi - 3
pKi 8.5 – 9.3 [3]
CCR1 Hs Agonist Full agonist 6.8 – 8.2 pKi - 2,4
pKi 6.8 – 8.2 [2,4]
CXCR3 Hs Agonist Full agonist 6.4 pKi - 11
pKi 6.4 [11]
GPR75 Hs Agonist Full agonist 9.6 pEC50 - 5
pEC50 9.6 (EC50 2.6x10-10 M) [5]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment