butorphanol

Ligand id: 7591

Name: butorphanol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 43.7
Molecular weight 327.22
XLogP 3.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
κ receptor Agonist Partial agonist 9.9 pKi - 1
pKi 9.9 (Ki 1.2x10-10 M) [1]
Description: Displacement of [3H]U69593 from human κ opioid receptor expressed in CHO cells.
μ receptor Agonist Partial agonist 9.9 pKi - 1
pKi 9.9 (Ki 1.2x10-10 M) [1]
Description: Displacement of [3H]DAMGO from human μ opioid receptor expressed in CHO cells.