AZD5672

Ligand id: 7686

Name: AZD5672

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 12
Topological polar surface area 111.83
Molecular weight 639.26
XLogP 4.89
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
CCR5 Antagonist Antagonist 9.6 pIC50 - 1
pIC50 9.6 (IC50 2.6x10-10 M) [1]
Description: Displacement of [125I]MIP-1α from human recombinant CCR5 expressed in CHO cells