AZD1208

Ligand id: 7698

Name: AZD1208

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 100.73
Molecular weight 379.14
XLogP 4.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Pim-1 proto-oncogene, serine/threonine kinase Inhibitor Inhibition 10.8 pKi - 1
pKi 10.8 (Ki 1.7x10-11 M) [1]
Pim-2 proto-oncogene, serine/threonine kinase Inhibitor Inhibition 9.8 pKi - 1
pKi 9.8 (Ki 1.6x10-10 M) [1]
Pim-3 proto-oncogene, serine/threonine kinase Inhibitor Inhibition 9.6 pKi - 1
pKi 9.6 (Ki 2.3x10-10 M) [1]