AZD5582

Ligand id: 7710

Name: AZD5582

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 16
Hydrogen bond donors 6
Rotatable bonds 24
Topological polar surface area 199.54
Molecular weight 1014.59
XLogP 8.37
No. Lipinski's rules broken 4

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
X-linked inhibitor of apoptosis Antagonist Antagonist 7.8 pIC50 - 1
pIC50 7.8 (IC50 1.5x10-8 M) [1]
baculoviral IAP repeat containing 2 Antagonist Antagonist 7.8 pIC50 - 1
pIC50 7.8 (IC50 1.5x10-8 M) [1]
baculoviral IAP repeat containing 3 Antagonist Antagonist 7.7 pIC50 - 1
pIC50 7.7 (IC50 2.1x10-8 M) [1]