AZD7762

Ligand id: 7713

Name: AZD7762

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 124.49
Molecular weight 362.12
XLogP 2.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
checkpoint kinase 1 Inhibitor Inhibition 8.3 pIC50 - 1
pIC50 8.3 (IC50 5x10-9 M) [1]
checkpoint kinase 2 Inhibitor Inhibition >8.0 pIC50 - 1
pIC50 >8.0 (IC50 <1x10-8 M) [1]