compound 38 [PMID: 22123324]

Ligand id: 7757

Name: compound 38 [PMID: 22123324]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 63.29
Molecular weight 466.27
XLogP 6.45
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
MCH2 receptor Antagonist Antagonist 9.0 pIC50 - 1
pIC50 9.0 (IC50 1x10-9 M) [1]