cilnidipine

Ligand id: 7767

Name: cilnidipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 117
Molecular weight 492.19
XLogP 8.03
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat ion channels
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Target Type Action Affinity Units Concentration range (M) Reference
Cav2.2 Channel blocker Pore blocker 6.7 pIC50 - 1
pIC50 6.7 [1]
Voltage: -60.0 mV