BMS-690514

Ligand id: 7879

Name: BMS-690514

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 100.94
Molecular weight 368.2
XLogP 1.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
epidermal growth factor receptor Inhibitor Inhibition 8.3 pIC50 - 2
pIC50 8.3 (IC50 5x10-9 M) [2]
erb-b2 receptor tyrosine kinase 2 Inhibitor Inhibition 7.7 pIC50 - 2
pIC50 7.7 (IC50 1.9x10-8 M) [2]
kinase insert domain receptor Inhibitor Inhibition 7.3 pIC50 - 2
pIC50 7.3 (IC50 5x10-8 M) [2]
fms related tyrosine kinase 3 Inhibitor Inhibition 7.0 pIC50 - 2
pIC50 7.0 (IC50 1.1x10-7 M) [2]