Synonyms: S7330
Compound class:
Synthetic organic
Comment: This compound exists in the trifluoroacetic acid form (PubChem CID 86208069). 6H05 is a selective allosteric inhibitor of oncogenic KRASG12C [1]. 6H05 was used as the reference compound in the development of K-Ras(G12C) inhibitor 6, K-Ras(G12C) inhibitor 9 and K-Ras(G12C) inhibitor 12 [1].
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Bioactivity Comments |
Due to the nature of the binding mode of this compound, affinity constants cannot be determined [1]. |