compound 34 [PMID: 24749861]

Ligand id: 8129

Name: compound 34 [PMID: 24749861]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 116.71
Molecular weight 287.09
XLogP 1.76
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
endoplasmic reticulum to nucleus signaling 1 Inhibitor Inhibition 7.3 pIC50 - 1
pIC50 7.3 (IC50 4.7x10-8 M) [1]
Description: Inhibition of RNAse activity.