compound 24 [PMID: 15955699]

Ligand id: 8131

Name: compound 24 [PMID: 15955699]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 110.92
Molecular weight 328.18
XLogP -0.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
ribosomal protein S6 kinase A5 Inhibitor Inhibition 8.9 pIC50 - 1
pIC50 8.9 (IC50 1.4x10-9 M) [1]