compound 2c [PMID: 22115617]

Ligand id: 8140

Name: compound 2c [PMID: 22115617]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 58.36
Molecular weight 530.74
XLogP 3.14
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
casein kinase 2, alpha prime polypeptide subunit Inhibitor Inhibition 7.7 pKi - 1
pKi 7.7 (Ki 2.1x10-8 M) [1]
casein kinase 2, alpha 1 polypeptide subunit Inhibitor Inhibition 7.1 pKi - 1
pKi 7.1 (Ki 8.3x10-8 M) [1]