compound 77 [PMID: 24793884]

Ligand id: 8217

Name: compound 77 [PMID: 24793884]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 145.25
Molecular weight 361.04
XLogP 1.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
cell division cycle 7 Hs Inhibitor Inhibition 8.2 pIC50 - 1
pIC50 8.2 (IC50 6.81x10-9 M) [1]
cyclin dependent kinase 18 Hs Inhibitor Inhibition - - - 1
Description: Measured as % inhibition using 1μM compound.