example 373 [WO2012093101]

Ligand id: 8296

Name: example 373 [WO2012093101]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 142.48
Molecular weight 524.14
XLogP 1.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
complement factor D Hs Inhibitor Inhibition 9.0 pIC50 - 1-2
pIC50 9.0 (IC50 1x10-9 M) [1-2]