seribantumab   Click here for help

GtoPdb Ligand ID: 8297

Synonyms: MM-121 | SAR256212
Compound class: Antibody
Comment: Seribantumab is a fully humanised IgG2 monoclonal antibody targeting ERBB3 (HER3) [1].
Peptide sequences for this antibody are available from its IMGT/mAb-DB record.
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Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
erb-b2 receptor tyrosine kinase 3 Primary target of this compound Hs Antibody Binding 9.1 pKd - 1
pKd 9.1 (Kd 7.69x10-10 M) [1]