CXCL7   Click here for help

GtoPdb Ligand ID: 830

Synonyms: PPBP
Immunopharmacology Ligand
Comment: CXCL7 (neutrophil-activating peptide 2, NAP-2) is one of the cleavage products of the pro-platelet basic protein (PPBP) gene. Connective tissue activating protein III and beta-thrombogulin are also products of this gene.
Species: Human
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Natural/Endogenous Targets
Target
CXCR2
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CXCR2 Ligand is endogenous in the given species Hs Agonist Full agonist 6.3 – 9.3 pIC50 - 1
pIC50 6.3 – 9.3 [1]