compound 7d [PMID: 25703523]

Ligand id: 8304

Name: compound 7d [PMID: 25703523]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 89.71
Molecular weight 319.01
XLogP 1.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
bromodomain containing 4 Inhibitor Inhibition 5.3 pKd - 1
pKd 5.3 (Kd 4.651x10-6 M) [1]