azeliragon

Ligand id: 8317

Name: azeliragon

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 14
Topological polar surface area 39.52
Molecular weight 531.27
XLogP 9.44
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
advanced glycosylation end-product specific receptor Antagonist Antagonist ~6.0 pIC50 - 3-4
pIC50 ~6.0 (IC50 ~1x10-6 M) [3-4]