compound 8a [PMID: 24900283]

Ligand id: 8503

Name: compound 8a [PMID: 24900283]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 70.68
Molecular weight 489.17
XLogP 8.27
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
BB3 receptor Hs Agonist Agonist 8.9 pIC50 - 1
pIC50 8.9 (IC50 1.4x10-9 M) [1]