compound 24dd [PMID: 20684603]

Ligand id: 8550

Name: compound 24dd [PMID: 20684603]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 98.2
Molecular weight 454.11
XLogP 3.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
dipeptidyl peptidase 4 Inhibitor Inhibition 8.9 pKi - 1
pKi 8.9 (Ki 1.4x10-9 M) [1]
dipeptidyl peptidase 9 Inhibitor Inhibition 6.7 pKi - 1
pKi 6.7 (Ki 1.9x10-7 M) [1]
dipeptidyl peptidase 8 Inhibitor Inhibition 6.6 pKi - 1
pKi 6.6 (Ki 2.7x10-7 M) [1]