compound 10 [PMID: 18790648]

Ligand id: 8665

Name: compound 10 [PMID: 18790648]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 5
Rotatable bonds 20
Topological polar surface area 207.95
Molecular weight 728.24
XLogP 8.25
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
MMP11 Hs Inhibitor Inhibition 6.6 pKi - 1
pKi 6.6 (Ki 2.3x10-7 M) [1]