Ligand id: 8721

Name: CCG-4986

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 126.46
Molecular weight 373.98
XLogP 2.45
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
regulator of G-protein signaling 4 Hs Inhibitor Inhibition 4.7 – 5.4 pIC50 - 1-3
pIC50 4.7 – 5.4 (IC50 1.8x10-5 – 4.2x10-6 M) [1-3]
Description: Inhibition of Gαo binding.