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Compound class:
Antibody
Comment: IGN523 is a humanized anti-CD98 (SLC3A2) monoclonal antibody being investigated as a potential therapy for acute myeloid leukemia (AML) [1-2].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| Bioactivity Comments |
| The affinity data in the table below is that reported in WO2013078377 A1 for the humanized clone 8-34B H2 L1 clone [2]. |
| Selectivity at transporters | ||||||||||||||||||||||||||||||||||
| Key to terms and symbols | Click column headers to sort | |||||||||||||||||||||||||||||||||
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