compound 35 [PMID: 23916259]

Ligand id: 8842

Name: compound 35 [PMID: 23916259]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 91.55
Molecular weight 441.22
XLogP 4.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mitogen-activated protein kinase 8 Inhibitor Inhibition 7.0 pIC50 - 1
pIC50 7.0 (IC50 9.2x10-8 M) [1]
Microtubule associated serine/threonine kinase 3 Inhibitor Inhibition 6.6 pIC50 - 1
pIC50 6.6 (IC50 2.4x10-7 M) [1]