lorglumide

Ligand id: 891

Name: lorglumide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 16
Topological polar surface area 86.71
Molecular weight 458.17
XLogP 5.82
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Parameter Concentration range (M) Reference
CCK1 receptor Rn Antagonist Antagonist 6.7 – 8.2 pIC50 - 2-3
pIC50 6.7 – 8.2 (IC50 1.99x10-7 – 6.31x10-9 M) [2-3]
CCK2 receptor Hs Antagonist Antagonist 5.5 pIC50 - 1
pIC50 5.5 [1]