Ligand id: 9025

Name: 852A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 111.28
Molecular weight 361.16
XLogP 2.45
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
TLR7 Hs Agonist Agonist 5.6 pEC50 - 4
pEC50 5.6 (EC50 2.657x10-6 M) [4]
TLR7 Mm Agonist Agonist 5.2 pEC50 - 4
pEC50 5.2 (EC50 6.224x10-6 M) [4]