852A

Ligand id: 9025

Name: 852A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 111.28
Molecular weight 361.16
XLogP 2.45
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
TLR7 Agonist Agonist 5.6 pEC50 - 4
pEC50 5.6 (EC50 2.657x10-6 M) [4]
Selectivity at mouse catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
TLR7 Agonist Agonist 5.2 pEC50 - 4
pEC50 5.2 (EC50 6.224x10-6 M) [4]