nabilone

Ligand id: 9071

Name: nabilone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 46.53
Molecular weight 372.27
XLogP 6.84
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Nabilone is in effect non-selective, exhibiting less than 2-fold selectivity for CB1 over CB2 [1].
Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
CB1 receptor Agonist Agonist 8.4 pKi - 1
pKi 8.4 (Ki 3.98x10-9 M) [1]
CB2 receptor Agonist Agonist 8.2 pKi - 1
pKi 8.2 (Ki 6.31x10-9 M) [1]
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