pindolol

Ligand id: 91

Name: pindolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 57.28
Molecular weight 248.15
XLogP 1.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
β2-adrenoceptor Hs Agonist Partial agonist 9.4 pKi - 2
pKi 9.4 (Ki 4x10-10 M) [2]
β1-adrenoceptor Hs Agonist Partial agonist 9.3 pKi - 2
pKi 9.3 (Ki 5.2x10-10 M) [2]
5-HT1A receptor Hs Antagonist Antagonist 8.1 pKi - 3
pKi 8.1 [3]
5-HT2B receptor Hs Agonist Full agonist 5.7 pKi - 1
pKi 5.7 [1]
5-HT2B receptor Hs Antagonist Antagonist 5.7 pKi - 1
pKi 5.7 [1]
5-HT2A receptor Hs Agonist Full agonist 5.0 pKi - 1
pKi 5.0 [1]
5-HT2A receptor Hs Antagonist Antagonist 5.0 pKi - 1
pKi 5.0 [1]