pindolol

Ligand id: 91

Name: pindolol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 57.28
Molecular weight 248.15
XLogP 1.62
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
β2-adrenoceptor Agonist Partial agonist 9.4 pKi - 2
pKi 9.4 (Ki 4x10-10 M) [2]
β1-adrenoceptor Agonist Partial agonist 9.3 pKi - 2
pKi 9.3 (Ki 5.2x10-10 M) [2]
5-HT1A receptor Antagonist Antagonist 8.1 pKi - 3
pKi 8.1 [3]
5-HT2B receptor Agonist Full agonist 5.7 pKi - 1
pKi 5.7 [1]
5-HT2B receptor Antagonist Antagonist 5.7 pKi - 1
pKi 5.7 [1]
5-HT2A receptor Agonist Full agonist 5.0 pKi - 1
pKi 5.0 [1]
5-HT2A receptor Antagonist Antagonist 5.0 pKi - 1
pKi 5.0 [1]