compound 4 [PMID: 27074625]

Ligand id: 9148

Name: compound 4 [PMID: 27074625]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 16
Topological polar surface area 125.21
Molecular weight 629.24
XLogP 5.21
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
FFA1 receptor Hs Agonist Agonist 8.1 – 8.4 pKd - 1
pKd 8.1 – 8.4 (Kd 7.4x10-9 – 4x10-9 M) [1]