olaratumab

Ligand id: 9172

Name: olaratumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Patent US8128929 reports preclinical experimental results of the in vitro and in vivo effects of olaratumab [1].
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
platelet derived growth factor receptor alpha Hs Antibody Binding 10.4 pKd - 1
pKd 10.4 (Kd 4x10-11 M) [1]
Description: BIAcore assay
platelet derived growth factor receptor alpha Hs Antibody Binding 9.2 pIC50 - 1
pIC50 9.2 (IC50 5.8x10-10 M) [1]
Description: Cellular assay