compound 18c [PMID: 25901531]

Ligand id: 9227

Name: compound 18c [PMID: 25901531]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 106.95
Molecular weight 410.08
XLogP 3.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
heat shock protein 90 beta family member 1 Hs Inhibitor Inhibition 6.7 pIC50 - 1
pIC50 6.7 (IC50 2.2x10-7 M) [1]