AM6538

Ligand id: 9338

Name: AM6538

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 102.53
Molecular weight 541.13
XLogP 6.46
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
CB1 receptor Antagonist Antagonist 8.3 pKi - 1
pKi 8.3 (Ki 4.6x10-9 M) [1]
Description: Competition binding assay using [3H]-CP55,940