ACT-389949

Ligand id: 9511

Name: ACT-389949

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 111.87
Molecular weight 428.14
XLogP 4.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
FPR2/ALX Hs Agonist Agonist 8.5 pEC50 - 1
pEC50 8.5 (EC50 3x10-9 M) [1]
Description: FPR2/ALX internalization into monocytes.