Ligand id: 953

Name: pramipexole

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: pramipexole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 79.18
Molecular weight 211.11
XLogP 1.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
D3 receptor Agonist Full agonist 8.4 – 8.7 pKi - 1-2
pKi 8.4 – 8.7 [1-2]
D2 receptor Agonist Full agonist 5.1 – 7.4 pKi - 1-2
pKi 5.1 – 7.4 [1-2]