IgE heavy chain   Click here for help

GtoPdb Ligand ID: 9557

Immunopharmacology Ligand
Comment: This entity is in the GtoPHARMACOLOGYdb and GtoImmuPdb as both a ligand (of the Fcε receptors) and as a target (target of anti-IgE monoclonal antibodies- see IGHE).
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Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Fc fragment of IgE receptor Ia Primary target of this compound Hs Agonist Binding 10.0 pKd -
pKd 10.0 (Kd 1x10-10 M)
Fc fragment of IgE receptor II Primary target of this compound Hs Agonist Binding 7.0 pKd -
pKd 7.0 (Kd 1x10-7 M)