NNC0640

Ligand id: 9574

Name: NNC0640

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 158.42
Molecular weight 573.22
XLogP 7.77
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
glucagon receptor Allosteric modulator Negative 7.2 pIC50 - 1
pIC50 7.2 (IC50 6.92x10-8 M) [1]